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Parkinson's Disease

Auteur Serge Przedborski
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Parkinson's Disease
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Parkinson's Disease
Parkinson's Disease
Als nieuw
73,00
10000449181
ISBN
9781936113323
Bindwijze
Hardcover
Taal
Engels
Auteur
Serge Przedborski
Uitgeverij
Cold Spring Harbor Laboratory Press,U.S.
Jaar van uitgifte
2012
Aantal pagina's
406

Waar gaat het over?

Parkinson's Disease is an incurable neurodegenerative disease characterized by a progressive loss of dopaminergic neurons that leads to slowness of movement, muscle rigidity, and tremors. Insoluble aggregates of proteins such as alpha-synuclein accumulate in the affected neurons, which also appear to be subject to oxidative stress. This volume discusses recent work that has begun to uncover the molecular mechanisms that underlie the condition, including studies that implicate dysfunction of mitochondrial proteins such as parkin and pink1.
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